About The Book

Noncardiac chest pain (NCCP) remains an enigmatic condition that continues to represent a major challenge not only to modern gastroenterology, but also the fields of cardiology and psychiatric medicine. It is a poorly understood and heterogeneous condition with numerous underlying potential mechanisms. Limited progress has been made in recent years, however, there is a dearth of good quality clinical studies, pathophysiological research as well as population and hospital epidemiological data. Noncardiac chest pain is a very common and debilitating condition which impacts greatly on individual’s both physically and psychosocially. The most complex and difficult aspects of noncardiac chest pain remain its diagnosis and management.

This is the first and only book to provide a comprehensive review of non-cardiac chest pain. Gathered here are the current world authorities in the field who have provided their insights and expertise on a variety of topics including epidemiology, cardiologist’s perspective, pathophysiology, non esophageal causes, sensory testing, psychological disorders, diagnosis, use of proton-pump inhibitors, brain imaging, economics, treatment, quality of life, prognosis and future developments.

About The Authors

Ronnie Fass, MD, is a Professor of Medicine at the University of Arizona in Tucson, Director of the GI Motility Laboratory at the University of Arizona Health Sciences Center and head of The Neuro-Enteric Clinical Research Group. Dr. Fass earned his medical degree at the Faculty of Health Sciences, Ben-Gurion University in Beer-Sheva, Israel and completed a one-year internship at Tel-Aviv University. He later moved to the USA and did his internship and residency in internal medicine at the University of Arizona Health Sciences Center, where he later became a Chief Resident. He then completed a fellowship in gastroenterology at the University of California in Los Angeles where he focused on GI motility and functional bowel disorders under the mentorship of Emeran Mayer, MD. He supplemented his GI motility at the Mayo Clinic in Rochester, MN, under the mentorship of Michael Camilleri, MD. Dr. Fass is a member of several professional organizations, including the American College of Gastroenterology, the American Gastroenterological Association and the American Motility Society. He is also involved with national committees and he is currently the chair of the Publication Committee of the American Society of Gastrointestinal Endoscopy (ASGE) and the American College of Gastroenterology Practice Parameter Committee. Dr. Fass is the recipient of the American Gastroenterological Association/Janssen Award for Digestive Sciences in Clinical or Basic Research and the Department of Veteran Affairs, Investigator of the Year award (2004). A frequent lecturer and presenter, Dr. Fass is a reviewer for 50 journals and is on the editorial board for 12 journals. He has published more than 350 abstracts, editorials, letters and articles in journals such as Gastroenterology, Gut, American Family Physician, American Journal of Gastroenterology and Archives of Internal Medicine.

Dr. Eslick is a Clinical Epidemiologist and National Health and Medical Research Council (NHMRC) Public Health Fellow in the School of Public Health at The University of Sydney, Australia. Dr. Eslick has an international reputation in the field on noncardiac chest pain, which he has been researching for over a decade. Dr. Eslick has over 100 publications, is an Associate Editor of the American Journal of Epidemiology, and serves on the Editorial Board of the World Journal of Gastroenterology.

Table Of Contents

  • Table of Contents
  • Epidemiology
    Guy Eslick;
  • Evaluation of Chest Pain: A Cardiology Perspective for Gastroenterologist
    Paul Fenster and Vincent L. Sorrell;
  • Pathophysiology of Noncardiac Chest Pain
    Ronnie Fass, Jae Geun Hyun, and Justin L. Sewell;
  • Non-cardiac, Non-esophageal Causes of Chest Pain
    Sami R. Achem and Ken R. DeVault;
  • Sensory Testing in Non Cardiac Chest Pain
    Abhishek Sharma and Qasim Aziz;
  • Psychological Disorders
    Guy D. Eslick;
  • Diagnosis of Non-Cardiac Chest Pain
    Elisa M. Faybush and Ronnie Fass;
  • The Proton Pump Inhibitor(PPI) Therapeutic Trial
    Wai-Man Wong and Ronnie Fass;
  • Brain Imaging in Non-Cardiac Chest Pain
    Anthony R. Hobson and Qasim Aziz;
  • Treatment
    Michael Shapiro, Anmarie Moore, and Ronnie Fass;
  • Economics (Direct and Indirect Costs)
    Guy D. Eslick;
  • Quality of Life
    Guy D. Eslick;
  • Prognosis
    Guy D. Eslick;
  • The Future
    Ronnie Fass.


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